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Study ID Status Title Patient Level Data
PGA105446 Completed Clinical Evaluation of 506U78 in Japanese Patients with Relapsed or Refractory T-cell Acute Lymphoblastic Leukemia or T-cell Lymphoblastic Lymphoma.
PHX111427 Completed A Phase I, Randomized, Single-Blind, Placebo-Controlled, Dose-Escalation Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of Single Oral Doses of GSK1278863A in Healthy Subjects
PIK111051 Terminated A Phase I Open-Label, Dose-Escalation Study of the Phosphoinositide 3-Kinase Inhibitor GSK1059615 in Patients with Solid Tumors or Lymphoma Study Listed on ClinicalStudyDataRequest.com
PIR104776 Completed Clinical Evaluation of BRL29060A (Paroxetine Hydrochloride Hydrate) in Social Phobia/Social Anxiety Disorder (SAD) A Double-blind, Placebo-controlled Study
PIR104777 Completed Clinical Evaluation of BRL29060A (Paroxetine Hydrochloride Hydrate) in Social Phobia/Social Anxiety Disorder (SAD) -A Open-Label, Uncontrolled, Long-term Study-
PIR109164 Terminated Clinical Evaluation of BRL29060A (Paroxetine Hydrochloride Hydrate) in Posttraumatic Stress Disorder (PTSD) - A Placebo-controlled, Single-Blind Comparative Study - Study Listed on ClinicalStudyDataRequest.com
PKI108574 Terminated A randomized, double blind, placebo controlled study to explore the antidepressant properties of P38a Kinase inhibitor GW856553X 15mg compared to PBO in Subjects with Major Depressive Disorder exhibiting symptoms of loss of energy and interest and psychomotor retardation, for a six week treatment period Study Listed on ClinicalStudyDataRequest.com
PLK107427 Completed A Phase I Study to Determine the Safety, Pharmacokinetics, and Pharmacodynamics of [GSK461364], a Polo-like Kinase 1 (PLK1) Inhibitor, in Adult Subjects with Advanced Solid Tumor or Non-Hodgkins Lymphoma Study Listed on ClinicalStudyDataRequest.com
PM1106502 Completed A randomized, single blind, repeat dose, placebo-controlled, single-period, parallel group study to investigate the safety, tolerability and potential pharmacokinetic interactions between GW856553 and Rosuvastatin (10mg), when co-administered in healthy adult male subjects
PM1108357 Completed A Double-Blind, Placebo-Controlled, Parallel Study To Evaluate The Effects Of GW856553 On Endothelial Function/Vascular Compliance In Subjects With Dyslipidaemia.
PM1111138 Completed A double-blind, placebo-controlled, parallel group study to evaluate the effects of two regimens of GW856553, over a period of 3 month, on in-vivo macrophage activity, as assessed by FDG-PET/CT imaging, in the carotid arteries and aorta of subjects with established atherosclerosis Study Listed on ClinicalStudyDataRequest.com
PMK103351 Completed A 28-day, randomized, double-blind, placebo-controlled study to assess the safety, tolerability, anti-inflammatory effect and steady-state pharmacokinetics of SB-681323 (7.5 mg) in subjects with coronary heart disease (CHD) undergoing elective percutaneous coronary interventions (PCI)
RA1100849 Completed A randomised, parallel group, placebo-controlled, double blind study to assess the safety and tolerability of SB-681323 at 7.5mg daily dose for 28 days and its effect on the levels of serum C-reactive protein (CRP) in subjects with rheumatoid arthritis (RA)
RA1101607 Completed A placebo controlled study to evaluate the safety and tolerability of repeat doses of SB-681323 in patients receiving methotrexate for rheumatoid arthritis.
RA1104046 Completed A randomised, placebo-controlled, parallel group single dose study of SB681323 in patients with active RA to investigate the CRP dose response relationship
RA1107570 Completed A study to assess the safety and tolerability of SB-681323 administered via the intravenous route
RA3103718 Completed A randomized, double blind, placebo controlled study to investigate the safety and tolerability and clinical activity of 28 days of oral repeat dosing with GW856553 at 7.5mg BID in subjects with active rheumatoid arthritis on stable anti-rheumatic therapy.
RA3103730 Completed A randomised, placebo-controlled, parallel group single dose study of GW856553 in patients with active RA to investigate the C-Reactive Protein (CRP) dose response relationship
RA4102651 Completed An enabling study to investigate the correlation of biomarkers of the activity of inducible nitric oxide synthase (iNOS) with disease activity and treatment response in patients with rheumatoid arthritis(RA)
RA4104917 Completed A randomised, double-blind, placebo-controlled, parallel group study to investigate the safety, tolerability, pharmacokinetics and effect on synovial thickness and vascularity of 28 days repeat dosing of GW274150 or 7.5mg prednisolone in RA subjects. Study Listed on ClinicalStudyDataRequest.com
RES100767 Terminated A Study To Validate Key Therapeutic Targets and Characterise Their Response to Corticosteroids in Multiple Asthma Phenotypes
RES100769 Terminated A study to assess disease pathology and key therapeutic targets in severe asthma
RES101509 Completed An investigation to evaluate the technique of MRI as an assessment of the effect of anti-allergy drug treatment on internal nasal and sinus mucosal anatomy following intranasal allergen challenge in subjects with seasonal allergic rhinitis.
RES104031 Completed A Randomised (with Respect to Microplaque Treatment Positions), Single-Blind, Placebo-Controlled, Positive-Controlled, Microplaque Study to Assess the Effectiveness of a Topical Formulation of GW786034 in Patients with Chronic Plaque Psoriasis
RES106087 Completed A randomized, double-blind study of treatment with a known anti-inflammatory (prednisolone) to evaluate novel endpoints in patients with chronic obstructive pulmonary disease (COPD)

 

 

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GSK-sponsored clinical studies are those for which GSK is ultimately responsible for all aspects of the study even if some or all of these activities are transferred to another party.
GSK-sponsored clinical trials are those for which GSK is ultimately responsible for all aspects of the study even if some or all of these activities are transferred to another party.

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