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Study ID Status Title Patient Level Data
49653/002 Completed An Evaluation of the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of BRL 49653 after 10 Days Repeat Dosing to Obese Subjects
49653/004 Completed Investigation of the Effect of Food on the Pharmacokinetics of BRL 49653C in Healthy Male Volunteers
49653/005 Completed A Single Dose Study to Assess the Safety, Tolerability, Dose Proportionality and Food Effect of the Proposed Commercial Tablet Formulation of BRL 49653C in Healthy Volunteers
49653/006 Completed A 12-Week, Multicenter, Double-Blind, Placebo-Controlled, Dose Response Study Assessing the Safety, Tolerability, and Efficacy of BRL 49653C in Subjects with Non-Insulin Dependent Diabetes Mellitus (NIDDM)
49653/007 Completed An Evaluation of the Pharmacokinetics of a Single Oral Dose of BRL 49653C in Hemodialysis-Dependent Patients with End Stage Renal Disease Compared to Volunteers with Normal Renal Function
49653/008 Completed An Evaluation of the Safety, Tolerability, Pharmacokinetics and Protein Binding of BRL 49653C in Patients with Hepatic Impairment
49653/009 Completed A Multicentre, Open-Label Extension Study to Assess the Long-Term Safety, Tolerability and Efficacy of Rosiglitazone When Administered to Patients With Type 2 Diabetes Mellitus. Study Listed on ClinicalStudyDataRequest.com
49653/011 Completed A 26-Week Randomized, Double-blind, Multicenter, Placebo-Controlled, Comparison Study to Evaluate the Safety, Efficacy, and Tolerability of Rosiglitazone Therapy when Administered to Patients with Non-insulin Dependent Diabetes Mellitus (NIDDM)
49653/013 Completed A Study of the Effect of Age on the Pharmacokinetics of BRL 49653C in Healthy Volunteers.
49653/014 Completed A Study to Determine the Effect of BRL 49653C on Steady-State Pharmacodynamics and Pharmacokinetics of Glyburide in Non-Insulin Dependent Diabetic Patients
49653/015 Completed A Multicentre, Double-Blind, Placebo Controlled, Parallel Group Comparative Study to Evaluate the Efficacy, Safety and Tolerability of Rosiglitazone with Concurrent Sulphonylurea therapy, When Administered to Patients with Type 2 Diabetes Mellitus. Study Listed on ClinicalStudyDataRequest.com
49653/016 Completed Evaluation of the Safety, Tolerability and Pharmacokinetics of Single Rising Oral Doses of 5, 10, 15 and 20 mg BRL 49653C in Healthy Male Volunteers
49653/017 Completed A Placebo-Controlled Single-Blind Study on the Safety, Tolerance and Pharmacokinetics of BRL49653C 1 mg, 2 mg, 4 mg, 8 mg and 16 mg in Single Oral Administration in Healthy Volunteers
49653/018 Completed Phase I Clinical investigation of 49653 (Series 2): A study on the effect of a Meal on the Pharmacokinetics of 49653 4 mg Administered Orally to Healthy Adult Volunteers
49653/019 Completed A Placebo-controlled Single-blind Study on the Safety, Tolerance and Pharmacokinetics of Single and 7-day (t.i.d.) Repeat Oral Administration of 49653 2mg in Healthy Adult Volunteers
49653/020 Completed A Multicentre, Double-Blind, Parallel Group Comparative Study to Evaluate the Efficacy, Safety and Tolerability of Rosiglitazone vs. Glibenclamide Therapy, When Administered to Patients with Type 2 Diabetes Mellitus. Study Listed on ClinicalStudyDataRequest.com
49653/022 Completed A Double-Blind, Parallel Group Placebo-Controlled Study to Determine the Effects of Rosiglitazone on Insulin Resistance and Glucose Tolerance When Administered to Subjects with Impaired Glucose Tolerance.
49653/024 Completed A 26-week Randomized, Double-blind, Multicenter, Placebo-Controlled, Study to Evaluate the Safety, Efficacy, and Tolerability of Rosiglitazone Therapy When Administered to Patients with Non-insulin Dependent Diabetes Mellitus (NIDDM) Using a Once Daily Dosing Regimen, and to Determine the Therap ...
49653/025 Completed A Multicentre, Double-Blind, Parallel Group Study to Determine the Effects of Rosiglitazone on Insulin Sensitivity, Endothelial Function and Vascular Reactivity in Comparison With Metformin and Placebo When Administered to Patients With Non-insulin Dependent Diabetes Mellitus. Study Listed on ClinicalStudyDataRequest.com
49653/028 Completed Bioequivalence Study of the Final Market Formulation of BRL 49653C Compared to the Clinical Trials Formulation
49653/029 Completed Evaluation of the Safety, Tolerability and Preliminary Pharmacokinetics of Single Rising Intravenous Doses of BRL 49653C in Normal Volunteers
49653/030 Completed A Bioequivalence Study of BRL 49653C Proposed Final Market Tablet Formulation (formula AGAA) versus BRL 49653C Clinical Trials Capsule Formulation (formula AB-AA)
49653/031 Completed An Investigation of the Effect of BRL 49653C on the Safety, Tolerability and Pharmacokinetics of Oral Contraceptives in Healthy Female Volunteers
49653/033 Completed Placebo controlled, double-blind, trial to study the effect of 12 week treatment with BRL-49653C on glucose and insulin metabolism in obese patients with NIDDM
49653/034 Completed A Study to Assess the Effects of BRL 49653C on the Pharmacokinetics of Digoxin in Healthy Adult Males

 

 

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