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Study ID Status Title Patient Level Data
49653/014 Completed A Study to Determine the Effect of BRL 49653C on Steady-State Pharmacodynamics and Pharmacokinetics of Glyburide in Non-Insulin Dependent Diabetic Patients
49653/015 Completed A Multicentre, Double-Blind, Placebo Controlled, Parallel Group Comparative Study to Evaluate the Efficacy, Safety and Tolerability of Rosiglitazone with Concurrent Sulphonylurea therapy, When Administered to Patients with Type 2 Diabetes Mellitus. Study Listed on ClinicalStudyDataRequest.com
49653/016 Completed Evaluation of the Safety, Tolerability and Pharmacokinetics of Single Rising Oral Doses of 5, 10, 15 and 20 mg BRL 49653C in Healthy Male Volunteers
49653/017 Completed A Placebo-Controlled Single-Blind Study on the Safety, Tolerance and Pharmacokinetics of BRL49653C 1 mg, 2 mg, 4 mg, 8 mg and 16 mg in Single Oral Administration in Healthy Volunteers
49653/018 Completed Phase I Clinical investigation of 49653 (Series 2): A study on the effect of a Meal on the Pharmacokinetics of 49653 4 mg Administered Orally to Healthy Adult Volunteers
49653/019 Completed A Placebo-controlled Single-blind Study on the Safety, Tolerance and Pharmacokinetics of Single and 7-day (t.i.d.) Repeat Oral Administration of 49653 2mg in Healthy Adult Volunteers
49653/020 Completed A Multicentre, Double-Blind, Parallel Group Comparative Study to Evaluate the Efficacy, Safety and Tolerability of Rosiglitazone vs. Glibenclamide Therapy, When Administered to Patients with Type 2 Diabetes Mellitus. Study Listed on ClinicalStudyDataRequest.com
49653/022 Completed A Double-Blind, Parallel Group Placebo-Controlled Study to Determine the Effects of Rosiglitazone on Insulin Resistance and Glucose Tolerance When Administered to Subjects with Impaired Glucose Tolerance.
49653/024 Completed A 26-week Randomized, Double-blind, Multicenter, Placebo-Controlled, Study to Evaluate the Safety, Efficacy, and Tolerability of Rosiglitazone Therapy When Administered to Patients with Non-insulin Dependent Diabetes Mellitus (NIDDM) Using a Once Daily Dosing Regimen, and to Determine the Therap ...
49653/025 Completed A Multicentre, Double-Blind, Parallel Group Study to Determine the Effects of Rosiglitazone on Insulin Sensitivity, Endothelial Function and Vascular Reactivity in Comparison With Metformin and Placebo When Administered to Patients With Non-insulin Dependent Diabetes Mellitus. Study Listed on ClinicalStudyDataRequest.com
49653/028 Completed Bioequivalence Study of the Final Market Formulation of BRL 49653C Compared to the Clinical Trials Formulation
49653/029 Completed Evaluation of the Safety, Tolerability and Preliminary Pharmacokinetics of Single Rising Intravenous Doses of BRL 49653C in Normal Volunteers
49653/030 Completed A Bioequivalence Study of BRL 49653C Proposed Final Market Tablet Formulation (formula AGAA) versus BRL 49653C Clinical Trials Capsule Formulation (formula AB-AA)
49653/031 Completed An Investigation of the Effect of BRL 49653C on the Safety, Tolerability and Pharmacokinetics of Oral Contraceptives in Healthy Female Volunteers
49653/033 Completed Placebo controlled, double-blind, trial to study the effect of 12 week treatment with BRL-49653C on glucose and insulin metabolism in obese patients with NIDDM
49653/034 Completed A Study to Assess the Effects of BRL 49653C on the Pharmacokinetics of Digoxin in Healthy Adult Males
49653/035 Completed A Study to Assess The Effect of BRL 49653C on the Anticoagulant Effect of Warfarin in Healthy Male Volunteers
49653/036 Completed A Study to Determine the Effect of BRL 49653C on the Pharmacokinetics of Metformin in Healthy Male Volunteers
49653/037 Completed A Study to Assess the Effect of Ranitidine on the Bioavailability of BRL 49653C in Healthy Adult Males
49653/038 Completed An Evaluation of the Pharmacokinetics of a Single Oral Dose of BRL 49653C in Patients with Varying Degrees of Renal Insufficiency Compared to Volunteers with Normal Renal Function
49653/039 Completed An Investigation of the Effect of BRL 49653C on the Safety, Tolerability and Pharmacokinetics of Nifedipine in Healthy Volunteers
49653/040 Completed Effect of Acarbose on the Pharmacokinetics of BRL 49653C in Healthy Adult Volunteers
49653/041 Completed A Study to Evaluate the Effect of Ethanol Administration on the Pharmacodynamics of BRL 49653C in Chronically-Treated Type 2 Diabetic Patients
49653/043 Completed Placebo-controlled, Double-Blinded Trial to Study the Absorptive and Post-Absorptive Skeletal Muscle and Hepatic Metabolic Effects of BRL-49653C After 12 weeks Treatment in Patients with Non-Insulin Dependent Diabetes Mellitus
49653/044 Completed A 26-week Randomized, Double-Blind, Multicenter, Placebo-Controlled Study to Evaluate the Efficacy, Safety and Tolerability of BRL 49653C When Administered Twice Daily to Patients with Non-Insulin Dependent Diabetes Mellitus (NIDDM) Who Are Inadequately…

 

 

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GSK-sponsored clinical studies are those for which GSK is ultimately responsible for all aspects of the study even if some or all of these activities are transferred to another party.
GSK-sponsored clinical trials are those for which GSK is ultimately responsible for all aspects of the study even if some or all of these activities are transferred to another party.

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