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Study ID Status Title Patient Level Data
CR219039 Completed A dose ranging study to assess the effect of pre-treatment with a single dose of inhaled fluticasone propionate (2 mg, 0.5 mg) on lung inflammation following challenge with inhaled ozone and intermittent exercise in healthy volunteers, relative to placebo. Study Listed on
CR9108914 Terminated A Proof-of-Concept Study Of SB-751689 In Men And Post-menopausal Women With A Fractured Distal Radius Study Listed on
CR9108963 Terminated Study CR9108963: A 12-month, randomized, double-blind, parallel-group, placebo and active-controlled dose-range finding study of the efficacy and safety of SB-751689 in post-menopausal women with osteoporosis Study Listed on
CRH103002 Terminated An open-label, repeat-dose, single-sequence study to investigate the effects of once-daily repeat oral administration of GW876008 125mg on the pharmacokinetics of the combined oral contraceptive in female volunteers
CRH103390 Completed Study CRH103390: A 12 Week Flexible Dose Study of GW876008, Placebo and Active Control (Paroxetine) in the Treatment of Social Anxiety Disorder (SocAD)
CRH108571 Completed Double-blind, randomized, placebo and Alprazolam-controlled three-period crossover incomplete block design study to compare putative anxiolytic-like fRMI activity of GW876008 and GSK561679 after single-dose administration in subjects with Social Anxiety Disorder (SAD)
CRI103143 Completed A Phase IIa, single-centre, randomised, placebo-controlled, double-blind, three-period crossover study investigating the effects on gut autonomic responses of single administrations of either 20 mg or 200 mg GW876008, a CRF1 antagonist, to adult patients with irritable bowel syndrome
CRI105626 Completed A randomised, double-blind, placebo-controlled, crossover study to evaluate efficacy and safety of the CRF1 receptor antagonist GW876008 in patients with Irritable Bowel Syndrome
CRR110744 Completed Phase I, open label drug-drug interaction study in healthy volunteers to evaluate the effect of KALETRA (lopinavir-ritonavir) on GSK706769 pharmacokinetics and to evaluate the pharmacokinetics of a new oral formulation of GSK706769
CRR111382 Completed A Double-Blind, Randomized, Placebo-Controlled, Repeat Dose Escalation Study to Investigate the Safety, Tolerability and Pharmacokinetics of GSK706769 in Healthy Male and Female Subjects
CRS 105510 Completed A randomised, placebo-controlled, double-dummy, crossover design study to investigate the changes of fMRI BOLD activation induced by emotional activation paradigms following single doses of GSK561679 and lorazepam (comparator) in healthy subjects
CRS105511 Completed Placebo-Controlled, Randomized, Blinded, Double-Dummy, Crossover study to Investigate the Attenuation of ACTH Activation Induced by Metyrapone with a single dose of GSK561679 or Alprazolam in Healthy Volunteers
CRV110734 Completed A study to evaluate the safety and tolerability of SK&F-105517-D in patients with chronic heart failure- An open-label study to evaluate the safety and tolerability, pharmacokinetics and pharmacodynamics of SK&F-105517-D in patients with chronic heart failure (Phase I/II study) Study Listed on
CRZ107432 Completed A single blind, randomized, placebo controlled, crossover study to investigate the safety, tolerability and pharmacokinetics of single oral escalating doses of GSK586529 in healthy volunteers
CUC111342 Terminated An open label, 7-day repeat dose study to evaluate the pharmacodynamics of SB-656933-AAA in patients with Ulcerative Colitis. Study Listed on
CXA10017 Completed An open-label, non-randomised, single sequence study to investigate the effect of a New Chemical Entity (NCE) on the pharmacokinetic profile of digoxin in healthy subjects.
CXA100754 Completed An open-label, non-randomised study of 20 mg GW406381 single dose pharmacokinetics in healthy subjects and in volunteers with moderate hepatic impairment
CXA30007 Completed A Phase III, 12-week, Multicentre, Double-Blind, Double-Dummy, Randomised, Placebo - and Active Comparator - Contolled, Parallel Group Study to Investigate the Efficacy and Safety of GW406381 XXmg and YYmg Administered Orally Once Daily, in Adults with Osteoarthritis of the Knee
CXA30009 Completed A Phase III, 12-Week, Multicentre, Double-Blind, Randomised, Placebo- and Active Comparator-Controlled, Parallel Group Study to Investigate the Efficacy and Safety of GW406381, 5mg, 10mg, 25mg, and 50mg administered orally once daily, in Adults with Rheumatoid Arthritis
D2250298 Completed An irritation patch test of topical formulations containing aciclovir
D-23129-8001/8005/ 8017 Completed Long term efficacy and safety of orally administered D-23129 in patients with partial onset seizures (long-term extension of studies 8001 [200] and 8005 [201])
D-23129-8040 Completed Clinical trial to assess tolerability, safety and efficacy of orally administered retigabine in patients with bipolar affective disorders (acute mania). Open pilot study with a sequential group design
DAN106587 Completed A placebo controlled, single blind, randomised study investigating the safety, tolerability and Pharmacokinetics of repeated oral doses of GSK598809 in healthy male and female volunteers for 28 days.
DAN106593 Completed A randomized, double-bind, placebo controlled, two-way cross-over study to assess the effects of a single dose of GSK598809, a Selective DRD3 Antagonist, in Modulating Nicotine Reward Study Listed on
DAN107606 Completed A placebo-controlled, single-blind, randomised, human volunteer study investigating the tolerability and pharmacokinetics of escalating single oral doses of GSK598809 in smokers



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GSK-sponsored clinical trials are those for which GSK is ultimately responsible for all aspects of the study even if some or all of these activities are transferred to another party. is a database that provides summary protocol information for ongoing clinical trials. is a search portal provided by the International Federation of Pharamceutical Manufacturers & Associations (IFPMA).

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