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Study ID Status Title Patient Level Data
S3B30011 Completed A Twelve Week Randomized, Double-Blind, Placebo-Controlled Study of the Efficacy and Tolerability of Alosetron Hydrochloride 1mg Twice Daily for Control of Bowel Urgency in Females with Nonconstipated Irritable Bowel Syndrome
S3B30012 Completed A 6-Week Trial of Alosetron Hydrochloride 1mg Twice Daily as Empirical Therapy in Female Subjects With Symptoms of Non-Constipated Irritable Bowel Syndrome
S3B30013 Completed A 12-Week, Randomized, Double-Blind, Placebo-Controlled Study of Alosetron in Female Subjects With Alternating Diarrhea/Constipation Irritable Bowel Syndrome
S3B30015 Completed An 8-Week, Randomized, Double-Blind, Placebo-Controlled Study of Alosetron in Non-Constipated Adolescents With Irritable Bowel Syndrome
S3B30017 Completed A Multi-Centre Study to Determine the Efficacy and Safety of Alosetron 2mg BID in Female Subjects With Diarrhoea-Predominant Irritable Bowel Syndrome who do not Respond to Treatment With Alosetron 1mg BID
S3B30019 Completed A 16-week, Open-label, Safety Study of Alosetron in Non-Constipated Adolescents with Irritable Bowel Syndrome
S3B30020 Completed A 24-Week Randomized, Open Label Study of Healthcare Resource Use, Quality of Life, and Productivity With Alosetron 1mg Twice Daily Versus Traditional Therapy in Females with Irritable Bowel Syndrome Whose Predominant Bowel Symptom is Diarrhea
S3B30025 Completed A 24-Week Randomised, Double-Blind, Placebo-Controlled Study of Quality of Life With Alosetron 1mg bd Versus Placebo in Females With Non-Constipated Irritable Bowel Syndrome
S3B30026 Completed 8-Week, Multicenter, Randomized Double-Blind Trial on Nonconstipated Patients with Irritable Bowel Syndrome Treated with 1mg Alosetron Twice A Day Compared to 2mg Alosetron Once A Day.
S3B30028 Completed An International, Multi-centre, Randomised, Double-Blind, Placebo-Controlled, Parallel-Group, 12-Week Study of Alosetron 1mg BID in Female Subjects With Diarrhoea-Predominant Irritable Bowel Syndrome Within Asia Pacific
S3B30031 Completed An 8-Week, Randomized, Double-Blind, Placebo-Controlled, Study of Alosetron in Female Subjects With Non-Constipated Irritable Bowel Syndrome Who Show Therapeutic Response to Alosetron
S3B30040 Completed A Twelve-Week, Randomized, Double Blind, Placebo-Controlled, Parallel-Group Study to Assess the Safety and Efficacy of 0.5 mg QD, 1 mg QD and 1 mg BID of Alosetron in Female Subjects with Severe Diarrhea-predominant IBS Who Have Failed Conventional Therapy
S3B30048 Completed A 12-Week, Randomized, Double-Blind, Placebo- Controlled Study of PRN BID and Fixed Dosing Regimens of Alosetron in Female Subjects with Severe Diarrhea-Predominant Irritable Bowel Syndrome Who Have Failed Conventional Therapy
S3B40031 Completed A 12-Week, Randomized, Double-Blind, Placebo-Controlled Study of the Efficacy and Tolerability of Alosetron Hydrochloride 1mg Twice Daily for Control of Bowel Urgency in Females with Non-constipated Irritable Bowel Syndrome in an Independent Practitioner Association (IPA) Model
S3B40032 Completed An Observational Study to Assess Prevalence, Natural History, and Burden of Illness of Irritable Bowel Syndrome (IBS) in Clinical Practice and to Evaluate the Impact of Alosetron Treatment on Natural History and Burden of Illness in a Cohort of Females Whose Predominant Bowel Symptom is Diarrhea
S3B40040 Completed A Double-Blind, Placebo-Controlled, Randomised, 2-Way Crossover Study to Evaluate the Potential Inhibition of Alosetron Metabolism by Ketoconazole in Healthy Female Subjects
S3B40041 Completed A Double-Blind, Placebo-Controlled, Randomised, 2-Way Crossover Study to Evaluate the Potential Inhibition of Alosetron Metabolism by Fluvoxamine in Healthy Female Subjects
S3B40042 Completed A randomize, placebo-controlled, crossover study to measure the effect of alosetron on mucosal blood flow in female healthy volunteers and diarrhea-predominant IBS subjects
S3BA1001 Completed A Randomised, Placebo-Controlled, Repeat Dose, Double-Blind Two-Period, Cross-over Study to Compare ECG Changes and Pharmacokinetics of Cisapride Following 4 Days of Dosing With Cisapride 20mg QID with Placebo and with Alosetron 1mg BID in Healthy Male and Female Volunteers.
S3BA1002 Completed An Open-Label, Non-Randomized, Two-Period Crossover, Drug-Drug Interaction Study to Compare the Pharmacokinetics of MIN-OVRAL in Healthy Female Subjects When Administered Alone for 21 Days, and Following Co-Administration of Alosetron 1mg bid Orally for 21 Days.
S3BA1003 Completed A randomised, open label, two-way cross-over trial to evaluate colonic transit times following one week of mebeverine 135 mg tds plus alosetron 1 mg bd versus alosetron 1 mg bd in healthy female volunteers.
S3BA1004 Completed A Randomized, Double-Blind, Placebo-Controlled, Repeat Dose, Two Period, Crossover Study to evaluate the effect of alosetron (1mg po BID) on theophylline (THEO-DUR 200mg po BID) pharmacokinetics in healthy female volunteers.
S3BA1006 Completed A Double-Blind, Randomized, Placebo-Controlled, 2-Way Crossover Study to Determine the Effect of Alosetron 1mg BID on Cholecystokinin-Induced Colonic Motility and Abdominal Pain in IBS Patients
S3BA2001 Completed A 12-week, Dose-ranging, Double-blind, Placebo-controlled Study of Alosetron (GR68755) in Subjects with Irritable Bowel Syndrome
S3BA2002 Completed Characterization of Changes in Regional Brain Activity Associated With Sigmoid Sensitization in IBS Patients Using Positron Emission Tomography (PET) With and Without Alosetron Therapy

 

 

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